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(Seoul = Larose.VIP) Reporter Seonggan Han = Research has shown that smoking can cause ‘suicidal’ death of red blood cells.

The medical news portal News Medical Life Science reported on the 14th that Professor Marvin Schmidt’s research team at the Simulation Technology Cluster Support Center at the University of Stuttgart, Germany, analyzed data from a study (NAKO) involving 205,000 adults and revealed this fact. reported.

The research team intensively analyzed data from 2,023 people in the same group.

Of these, 418 were currently smoking, 1,000 had never smoked and 605 had previously smoked but had quit.

The research team specifically looked at whether there was a link between smoking habits and eryptosis.

Erythrocytosis refers to ‘suicidal’ red blood cell death, similar to apoptosis, which can be triggered by oxidative stress.

As a result, smokers showed slightly more red blood cell death than non-smokers and former smokers.

Smokers had 14% more dead red blood cells than non-smokers and 19% more than ex-smokers. There was no significant difference between non-smokers and former smokers.

There was also a relationship between the amount of smoking per day and the rate of red blood cell death. This was the same for both male and female smokers.

In former smokers, an inverse relationship was found between the period of time quitting smoking and the rate of red blood cell death.

The age at which one quit smoking and the time elapsed since quitting were found to be indicators of red blood cell death.

The research team also analyzed the effects of smoking on red blood cell death and hematological parameters (erythrocyte count, hematocrit, average red blood cell cell volume, average hemoglobin amount, and average hemoglobin concentration in blood cells).

Among hematological parameters, red blood cell count, hemoglobin, hematocrit, and mean blood cell volume were not associated with red blood cell death. The average blood cell hemoglobin amount and average blood cell hemoglobin concentration were slightly related to red blood cell death.

There was no significant difference in red blood cell count and hematocrit between smokers, non-smokers, and former smokers.

However, the average blood cell volume, average blood hemoglobin content, and average blood hemoglobin concentration were higher in smokers than in non-smokers and former smokers.

This suggests that red blood cell death in smokers does not have a negative effect on the overall red blood cell system, the research team said.

Oxidative stress and inflammation caused by smoking may be responsible for the death of red blood cells in smokers. The carbon monoxide you inhale when you smoke may directly stimulate red blood cell death.

It was found that although smokers have increased red blood cell death, their red blood cell count does not decrease significantly.

The research team explained that this may be because smokers have improved red blood cell production, which creates new red blood cells, thereby replenishing red blood cell loss due to red blood cell death.

Cigarettes contain many harmful substances such as nicotine, carbon monoxide, formaldehyde, acetaldehyde, and benzopyrene.

If these harmful substances are inhaled into the body and enter the bloodstream, they can cause cardiovascular problems. In particular, carbon monoxide combines with the hemoglobin of red blood cells to form carboxyhemoglobin, thereby reducing the oxygen carrying capacity of hemoglobin.

The results of this study were published in the latest issue of the British scientific journal ‘Scientific Reports’.

red blood cells

red blood cells

skhan@yna.co.kr

Report to KakaoTalk okjebo 2024/02/15 09:21 Sent

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