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‘CBD’, a hemp ingredient with little risk of abuse

Active development of formulations such as oral films and microneedle patches

growing hemp

growing hemp

(Seoul = Larose.VIP) Reporter Kim Hyun-soo = As the potential of the hemp-utilizing industry is gaining attention, domestic pharmaceutical and bio companies are also preparing for the ‘era of the hemp industry’ by researching formulations with increased convenience using hemp ingredients.

According to the pharmaceutical and bio industry on the 18th, CTC Bio, a pharmaceutical research and development company,[060590]Last year, participated in the Gyeongbuk Industrial Hemp Regulation-Free Special Zone national project and conducted research to convert cannabidiol (CBD), a hemp ingredient, into an orally dissolvable film (ODF) that melts in the mouth.

CBD is classified as a representative component of hemp along with tetrahydrocannabinol (THC).

Although the use of THC is limited due to its hallucinogenic effects, CBD has little risk of dependence or abuse, so it is used overseas as a medicine and food additive.

Epidiolex, an epilepsy treatment developed by British pharmaceutical company GW Pharmaceuticals, is a representative drug using CBD.Cannabis

CTC Bio explained that when CBD is taken in film form, the appropriate amount can be taken and various flavors can be added to make up for the shortcomings of CBD, which has a spicy taste.

The company is currently discussing ways to enter overseas markets based on its research results.

Yuhan Health & Living announced on the 14th that it and Endoderma, a microstructure patch cosmetics company, confirmed the safety of a microneedle patch (a patch with numerous fine needles) containing CBD in the United States in the first human skin irritation test.

An official from Yuhan Health Life said, “This is the result of research that sought a way out if commercialization of medical cannabis ingredients becomes possible in Korea in the future. We are working to improve the overseas competitiveness of the domestic cannabis industry, including research on formulations and safety to effectively deliver CBD to the human body. “I’m trying,” he said.

Epidiolex, medical hemp extract medicine

Epidiolex, medical hemp extract medicine

Currently, Korea regulates marijuana in accordance with the Narcotic Drugs Control Act, and academic research on marijuana ingredients requires permission from the Ministry of Food and Drug Safety. However, even if efficacy is proven in research, the product cannot be commercialized.

If you wish to import cannabis-based medicines, you can only do so through the Korea Orphan and Essential Medicines Center.

However, overseas, there are continued calls for easing regulations on CBD.

The World Health Organization (WHO) recommended easing regulations in 2018, saying there was no evidence that CBD use would cause public health problems, and the United Nations removed hemp from class 4 narcotics (the most dangerous and least medically valuable substance). There is a bar.

An official at the Gyeongbuk Bio Industry Research Institute said, “Companies that participated in the research in the Gyeongbuk Hemp Special Zone conducted various research using CBD last year, including cosmetics and acne treatments. Since CBD is effective for medical purposes, we are encouraging medical schools and pharmaceutical companies to conduct research on it.” “If regulations are relaxed, better research results will come out,” he said.

The Ministry of Food and Drug Safety, which is in charge of drug management, plans to allow domestic manufacturing and import of cannabis-based medicines in consideration of future social conditions, in a situation where strict management of narcotics is socially required.

Meanwhile, unlike CBD, which is mainly extracted from hemp leaves and flowers and is regulated as a narcotic in Korea, hemp seed oil is recognized as a food ingredient and is used in health functional foods. Hemp stems are also used in textiles and cosmetics.

Last year, Yuhan Health & Life Insurance launched the cosmetics brand ‘Hebua’, which is made with ‘Hebuarex’, which was developed by its affiliated research center by combining cannabis stem and root extract, as its main ingredient.

hyunsu@yna.co.kr

Report to KakaoTalk okjebo 2024/02/18 08:00 Sent

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