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genetic research

genetic research

(Seoul = Larose.VIP) Reporter Han Seong-gan = A study showed that if you have a breast cancer mutation gene (BRCA1 or BRCA2) that significantly increases the risk of breast cancer, you can prevent 80% of breast cancer with preventive mastectomy.

Women who carry the BRCA breast cancer mutation gene have an 80% chance of developing breast cancer in their lifetime, and preventive mastectomy is known to reduce the risk of breast cancer by up to 90%. In Canada, 30% of women with the BRCA mutation gene choose prophylactic mastectomy.

Professor Kelly Metcalfe’s research team at the Familial Breast Cancer Research Laboratory at the Women’s College Hospital in Canada conducted a study on 1,654 women with BRCA mutation genes, and this was revealed, according to the American Association for the Advancement of Science (AAAS). )’s science news site EurekAlert reported on the 19th.

Of these, 827 chose prophylactic mastectomy. The research team used another 827 people who did not have a mastectomy as a control group and followed them for an average of 6.3 years.

As a result, in the prophylactic mastectomy group, 20 people were diagnosed with breast cancer during the follow-up period, and 2 people died from breast cancer.

Of these, 15 had latent breast cancer in which only metastasis to the axillary lymph nodes was diagnosed, with no cancer diagnosed in the breast itself.

In the group that did not have prophylactic mastectomy, 100 people were diagnosed with breast cancer and 7 people died from breast cancer.

The research team explained that this shows that preventive mastectomy prevented the development of breast cancer by 80% and reduced death from breast cancer to less than 1% (0.95%).

For women with BRCA mutations, choosing prophylactic mastectomy is not an easy task.

The research team said that showing them more solid evidence would help them make decisions.

So far, the only study on this subject was published by a Dutch research team.

The results of this study were published in the latest issue of the British Journal of Cancer, an academic journal of Cancer Research UK (CRUK).

skhan@yna.co.kr

Report to KakaoTalk okjebo 2024/02/20 09:02 Sent

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